Australian & New Zealand Childrens Haematology/Oncology Group
Study Title
A Randomized, Double-Blinded, Pilot Trial of Neoadjuvant Checkpoint Inhibition followed by Combination Adjuvant Checkpoint Inhibition in Children and Young Adults with Recurrent or Progressive High Grade Glioma (HGG)
Protocol ID
PNOC 0019
Disease (Sub Disease)
Brain and Spinal Tumours (High Grade Gliomas)
Diagnosis Stage
Relapsed/ refractory
Sponsor
Australian and New Zealand Children's Haematology Oncology Group
Pacific Pediatric Neuro-Oncology Consortium
Pacific Pediatric Neuro-Oncology Consortium
Collaborators
Bristol-Myers Squibb
Links
Trial Status
Closed to Recruitment
Sites
Perth Children's Hospital
Sydney Children's Hospital
The Children's Hospital at Westmead
Queensland Children's Hospital
Royal Children's Hospital
Women's and Children's Hospital
Sydney Children's Hospital
The Children's Hospital at Westmead
Queensland Children's Hospital
Royal Children's Hospital
Women's and Children's Hospital
Study Type
Treatment
Phase
Pilot
Age Eligibility
6 Months to 22 Years
International registry ID's
NCT04323046
| Study Title | A Randomized Double-Blinded Pilot Trial of Neoadjuvant Checkpoint Inhibition followed by Combination Adjuvant Checkpoint Inhibition in Children and Young Adults with Recurrent or Progressive High Grade Glioma (HGG) |
|---|---|
| Protocol ID | PNOC 0019 |
| Disease (Sub Disease) | Brain and Spinal Tumours (High Grade Gliomas) |
| Diagnosis Stage | Relapsed/ refractory |
| Sponsor | Australian and New Zealand Children's Haematology Oncology Group/ Pacific Pediatric Neuro-Oncology Consortium |
| Collaborators | Bristol-Myers Squibb |
| Links | https://clinicaltrials.gov/ct2/show/NCT04323046 |
| Trial Status | Closed to Recruitment |
| Trial Open Date | 01/03/2021 |
| Sites | Perth Children's Hospital / Sydney Children's Hospital/ The Children's Hospital at Westmead/ Queensland Children's Hospital / Royal Children's Hospital / Women's and Children's Hospital |
| Study Type | Treatment |
| Phase | Pilot |
| Age Eligibility | 6 Months to 22 Years |
| International registry ID's | NCT04323046 |