Study Title
PNOC019: A Single Arm, Pilot of Neoadjuvant Checkpoint Inhibition followed by Adjuvant Checkpoint Inhibition in Children and Young Adults with Recurrent or Progressive High Grade Glioma (HGG)
Protocol ID
PNOC019
Condition/s
Glioblastoma
Malignant Glioma
Recurrent Glioblastoma
Recurrent Malignant Glioma
Recurrent Grade III Glioma
Grade III Glioma
Malignant Glioma
Recurrent Glioblastoma
Recurrent Malignant Glioma
Recurrent Grade III Glioma
Grade III Glioma
Diagnosis Stage
Relapsed/Recurrent
Location
NSW, QLD, VIC, WA, SA
Sponsor
Australian and New Zealand Children's Haematology Oncology Group
Pacific Pediatric Neuro-Oncology Consortium
Pacific Pediatric Neuro-Oncology Consortium
Collaborators
Bristol-Myers Squibb
Links
Trial Status
Open
Sites
Perth Children's Hospital
The Children's Hospital at Westmead
Queensland Children's Hospital
The Royal Children's Hospital
Women's and Children's Hospital, Adelaide
Sydney Children's Hospital
Monash Children's Hospital, Melbourne
The Children's Hospital at Westmead
Queensland Children's Hospital
The Royal Children's Hospital
Women's and Children's Hospital, Adelaide
Sydney Children's Hospital
Monash Children's Hospital, Melbourne
Study Type
Treatment
Phase
Pilot
Age Eligibility
6 Months to 22 Years
International registry ID's
NCT04323046
| Study Title | PNOC019: A Single Arm Pilot of Neoadjuvant Checkpoint Inhibition followed by Adjuvant Checkpoint Inhibition in Children and Young Adults with Recurrent or Progressive High Grade Glioma (HGG) |
|---|---|
| Protocol ID | PNOC019 |
| Disease (Sub Disease) | Glioblastoma Malignant Glioma Recurrent Glioblastoma Recurrent Malignant Glioma Recurrent Grade III Glioma Grade III Glioma |
| Diagnosis Stage | Relapsed/Recurrent |
| Location | NSW / QLD / VIC / WA / SA |
| Sponsor | Australian and New Zealand Children's Haematology Oncology Group/ Pacific Pediatric Neuro-Oncology Consortium |
| Collaborators | Bristol-Myers Squibb |
| Links | https://clinicaltrials.gov/ct2/show/NCT04323046 |
| Trial Status | Open |
| Trial Open Date | 01/03/2021 |
| Sites | Perth Children's Hospital / The Children's Hospital at Westmead/ Queensland Children's Hospital / The Royal Children's Hospital / Women's and Children's Hospital, Adelaide/ Sydney Children's Hospital / Monash Children's Hospital, Melbourne |
| Study Type | Treatment |
| Phase | Pilot |
| Age Eligibility | 6 Months to 22 Years |
| International registry ID's | NCT04323046 |