There is no effective treatment or cure for children diagnosed with Diffuse Intrinsic Pontine Glioma (DIPG). Current treatment for DIPG is radiation, which is, ultimately, ineffective. This trial will explore if existing chemotherapy drugs can be a safe and effective treatment. Initially the child will undergo a biopsy, performed by a specially trained neurosurgeon, to examine the unique biological characteristics of the child’s DIPG. This will determine which of the three chemotherapy drugs is given to the child during and after radiation. The data from the tissue samples and drug treatment studies will also help other children in the future.
Disease Stage: New Diagnosis
Patient Age Range: >6 months and <25 years
Sample Size: 250
Recruitment period: 4 years
- International: Institut Gustave-Roussy, France
- National: ANZCHOG