Blin-fant Study: A pilot study to test the feasibility, safety and efficacy of the addition of the BiTE antibody Blinatumomab to the Interfant-06 backbone in infants with MLL-rearranged acute lymphoblastic leukemia: A collaborative study of the Interfant network
Leukaemia: Acute lymphoblastic leukaemia (MLL rearranged)
Status:
Closed to Recruitment
This study will investigate the effectiveness of the introduction of a new drug Blinotumomab to the standard treatment for infants diagnosed with acute lymphoblastic leukaemia (ALL). Blinotumomab attaches to the cancer cells, causing them to break down and die. Infants will be given the standard chemotherapy treatment for the first month, followed by an additional month of continuous treatment with Blinotumomab. This will require an extra period of hospitalisation.
Disease Stage: Newly diagnosed
Patient Age Range: < 1year
Sample Size: 30
Trial Sponsors:
- International: Princess Maxima Center for Pediatric Oncology Netherlands
- National: ANZCHOG
