Some children and adolescents with ALL will require a bone marrow transplant. Prior to transplant, some patients will receive total body irradiation (TBI), which has a number of debilitating side effects for the patient. This study will examine whether a three-drug chemotherapy combination without TBI works as well as a single drug treatment with TBI. In addition this study will examine the impact of bone marrow transplant donor options on the child or adolescent’s outcomes.
Disease Stage: Remission
Patient Age Range: At diagnosis <18 years; age at transplant <21 years
Sample Size: 1000
Recruitment period: 5 years
- International: St. Anna Kinderkrebsforschung, Vienna, Austria
- National: ANZCHOG