ReRAD: A Phase II Canadian Paediatric Brain Tumour Consortium Study of Re – Irradiation as Treatment of Progressive or Recurrent Diffuse Intrinsic Pontine Glioma

Diffuse Intrinsic Pontine Glioma (DIPG) is an aggressive brain tumour with no effective treatment and no chance of long-term survival . When this brain tumour grows back after the initial radiation therapy, it is known as progressive or recurrent DIPG.

This study will investigate how long a second treatment with radiation (re-irradiation) keeps progressive or recurrent DIPG from growing again and the overall survival of these patients. All children enrolled will be treated with re-irradiation.

Disease stage: Progressive or Recurrent

Patient age range:  less than 18 years of age

Trial sponsors:

• National: ANZCHOG
• International: University of Calgary