Last Updated | 31 March 2026

CINC424F12201 / REACH4

A Phase I/II Open-label and Single-arm and Multi-center Study of Ruxolitinib Added to Corticosteroids in paediatric Patients With Grade II-IV Acute Graft vs. Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation
External Registry
Site Status
Queensland Children's Hospital (QLD)
John Hunter Children's Hospital (NSW)
Sydney Children's Hospital (NSW)
Monash Health Clayton (VIC)
Royal Children's Hospital (VIC)
Women's and Children's Hospital (SA)
Perth Children's Hospital (WA)
Royal Hobart Hospital (TAS)
Children's Hospital at Westmead (NSW)
Starship Children's Hospital (NZ)
Christchurch Hospital (NZ)
Preparing to Open
Open
Temporarily Closed
Closed
Complete
Adult Sites These sites are not monitored. Status may vary.
Diagnosis Stage Newly Diagnosed, Relapsed/Refractory
National Sponsor Novartis Pharmaceuticals
Open Date 23/08/2018
Conditions Acute Graft Versus Host Disease
Patient Range 28 days17 years
Disease Type Leukaemia / Lymphoma / Blood Disorders
Study Type Interventional
International Sponsor N/A

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