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Women's & Children's Hospital

Women’s and Children’s Hospital is South Australia’s specialist centre for paediatric cancer care, delivering integrated treatment, research and family support under one roof. With a strong emphasis on continuity of care from diagnosis through survivorship, the site contributes to clinical trials through the ANZCHOG network to improve outcomes for children and adolescents.

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Recruiting Trials

Open
Phase 3

AALL1732

A Phase 3 Randomized Trial of Inotuzumab Ozogamicin (NSC#: 772518) for Newly Diagnosed High-Risk B-ALL; Risk-Adapted Post-Induction Therapy for High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and Disseminated B-LLy
1 year

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25 years
Queensland Children’s Hospital, John Hunter Children’s Hospital, Monash Health Clayton, Royal Children’s Hospital, Women’s and Children’s Hospital, Perth Children’s Hospital, Royal Hobart Hospital, Starship Children’s Hospital, Christchurch Hospital
Leukaemia / Lymphoma / Blood Disorders
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Open
Phase 2

ACNS2021

A Phase 2 Trial of Chemotherapy Followed by Response-Based Whole Ventricular &Amp; Spinal Canal Irradiation (WVSCI) for Patients With Localized Non-Germinomatous Central Nervous System Germ Cell Tumor
3 years

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29 years
Queensland Children’s Hospital, Sydney Children’s Hospital, Royal Children’s Hospital, Women’s and Children’s Hospital, Perth Children’s Hospital, Children’s Hospital at Westmead, Starship Children’s Hospital, Christchurch Hospital
Brain and Spinal (Central Nervous System) Tumours
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Open
Phase 2

ACNS2321

A Phase II Trial Evaluating Chemotherapy followed by Response-Based Reduced Radiation Therapy for Patient with Central Nervous System Germinomas
3 years

|

29 years
Queensland Children’s Hospital, John Hunter Children’s Hospital, Sydney Children’s Hospital, Royal Children’s Hospital, Women’s and Children’s Hospital, Perth Children’s Hospital, Children’s Hospital at Westmead, Starship Children’s Hospital
Brain and Spinal (Central Nervous System) Tumours
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Open

ACOR

Australian Cardio-Oncology Registry
<35 years
John Hunter Children’s Hospital, Monash Health Clayton, Royal Children’s Hospital, Women’s and Children’s Hospital, Perth Children’s Hospital, Children’s Hospital at Westmead
, Brain and Spinal (Central Nervous System) Tumours, Digestive System Tumours, Endocrine Tumours, Eye Tumours, Female genital tumours, Genetic tumour syndromes, Germ Cell Tumours, Leukaemia / Lymphoma / Blood Disorders, Head and neck tumours, Neuroblastoma and Ganglioneuroblastoma, Kidney (Renal) Tumours, Skin tumours, Soft Tissue and Bone Tumours (Sarcoma), Chest and Lung (Thoracic) Tumours
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Open
Phase 3

ALLELE (ATA129-EBV-302)

Multicenter, Open Label, Phase 3 Study of Tabelecleucel for Solid Organ or Allogeneic Hematopoietic Cell Transplant Subjects with Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease after Failure of Rituximab or Rituximab and Chemotherapy
No limit
Royal Children’s Hospital, Women’s and Children’s Hospital, Children’s Hospital at Westmead
Leukaemia / Lymphoma / Blood Disorders
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Open
Phase 2

ANBL1821

A Phase 2 Randomised Study of Irinotecan/Temozolomide/Dinutuximab with or without Eflornithine (DFMO) (IND# TBD) in Children with Relapsed& Refractory or Progressive Neuroblastoma
>1 year
Queensland Children’s Hospital, Sydney Children’s Hospital, Royal Children’s Hospital, Women’s and Children’s Hospital, Perth Children’s Hospital
Neuroblastoma and Ganglioneuroblastoma
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Open

APEC14B1

Project: EveryChild A Registry and Eligibility Screening and Biology and Outcome Study
<25 years
Queensland Children’s Hospital, John Hunter Children’s Hospital, Sydney Children’s Hospital, Monash Health Clayton, Royal Children’s Hospital, Women’s and Children’s Hospital, Perth Children’s Hospital, Royal Hobart Hospital, Children’s Hospital at Westmead, Starship Children’s Hospital, Christchurch Hospital
Breast tumours, CNS tumours, Digestive system tumours, Endocrine tumours, Eye tumours, Female genital tumours, Genetic tumour syndromes, Germ cell tumours, Haematolymphoid disorders, Head and neck tumours, Peripheral neuroblastic tumours, Renal and male genital tumours, Skin tumours, Soft tissue and bone tumours, Thoracic tumours
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Open
Phase 2

CBYL719F12202 EPIK-P4

A Phase II single arm study to assess the efficacy, safety and pharmacokinetics of alpelisib (BYL719) in paediatric and adult patients with PIK3CA-related overgrowth spectrum (PROS)
2 years

|

100 years
Women’s and Children’s Hospital
Genetic tumour syndromes
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Open
Phase 2

DAY101-001 (FIREFLY)

A Phase 2, Open-Label, Multicenter Study to Evaluate the Safety and Efficacy of the Oral Pan-RAF Inhibitor DAY101 in paediatric Patients With BRAF-Altered, Recurrent or Progressive Low-Grade Glioma
6 months

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25 years
Queensland Children’s Hospital, Sydney Children’s Hospital, Women’s and Children’s Hospital, Children’s Hospital at Westmead
CNS tumours
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Open
Phase 3

Firefly-2

A Phase 3, Randomized, International Multicenter Trial of DAY101 Monotherapy Versus Standard of Care Chemotherapy in Patients With paediatric Low-Grade Glioma Harboring an Activating RAF Alteration Requiring First-Line Systemic Therapy
<25 years
Sydney Children’s Hospital, Women’s and Children’s Hospital, Perth Children’s Hospital, Children’s Hospital at Westmead, Starship Children’s Hospital
CNS tumours
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Closed to Recruitment
Phase 1/2

LOXO-TRK-15003

A Phase 1/2 Study of the Oral TRK Inhibitor LOXO-101 in Pediatric Patients With Advanced Solid or Primary Central Nervous System Tumors
<21 years
N/A
Breast tumours, CNS tumours, Digestive system tumours, Endocrine tumours, Eye tumours, Female genital tumours, Genetic tumour syndromes, Germ cell tumours, Haematolymphoid disorders, Head and neck tumours, Peripheral neuroblastic tumours, Renal and male genital tumours, Skin tumours, Soft tissue and bone tumours, Thoracic tumours
Learn More

ANZCHOG Hospital Sites

Australia & New Zealand · 11 Sites
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