rEECur is an international trial for both adults and children looking at different types of chemotherapy to treat Ewing’s Sarcoma that didn’t respond to treatment or has come back afterwards. It compares different chemotherapy combinations to find out which one is the most effective for treating relapsed cancer. By testing these treatments against each other in one study, researchers can quickly find clear answers for doctors and families on the most effective way to fight the disease again. This helps ensure that patients always receive the most effective medicine available based on the latest scientific evidence.
An international Phase II/III randomised controlled multi-arm, multi-stage (MAMS) trial for relapsed or refractory Ewing Sarcoma. It utilises a multi arm design to compare various chemotherapy regimens. The primary goal is to identify the most effective regimen based on objective response and progression free survival. This MAMS approach allows for the systematic evaluation of existing treatments and the seamless introduction of new agents, establishing a clear evidence based standard of care for relapsed Ewing Sarcoma.