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Australian & New Zealand Childrens Haematology/Oncology Group

ANZCHOG Children’s Cancer Clinical Trials Repository

Study Title
A Safety, Pharmacokinetic and Efficacy Study of a y-Secretase Inhibitor, Nirogacestat (PF-03084014) in Children and Adolescents With Progressive, Surgically Unresectable Desmoid Tumors
Protocol ID
ARST1921
Disease (Sub Disease)
Desmoid-Type Fibromatosis
Diagnosis Stage
New Diagnosis
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Location
WA
Sponsor
Children's Oncology Group
Collaborators
National Cancer Institute (NCI)
SpringWorks Therapeutics, Inc.
Trial Status
Open
Sites
Perth Children's Hospital
Study Type
Treatment
Phase
Phase 2
Age Eligibility
12 Months to 18 Years
International registry ID's
NCT04195399
Back to Registry
Study Title A Safety Pharmacokinetic and Efficacy Study of a y-Secretase Inhibitor Nirogacestat (PF-03084014) in Children and Adolescents With Progressive Surgically Unresectable Desmoid Tumors
Protocol ID ARST1921
Disease (Sub Disease) Desmoid-Type Fibromatosis
Diagnosis Stage New Diagnosis
Relapse
Location WA
Sponsor Children's Oncology Group
Collaborators National Cancer Institute (NCI)/ SpringWorks Therapeutics, Inc.
Links https://clinicaltrials.gov/ct2/show/NCT04195399
Trial Status Open
Trial Open Date 21/09/2020
Sites Perth Children's Hospital
Study Type Treatment
Phase Phase 2
Age Eligibility 12 Months to 18 Years
International registry ID's NCT04195399