Australian & New Zealand Childrens Haematology/Oncology Group

Clinical Trials

Viewing: Closed to Recruitment

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High Grade Glioma(NICHE-HGG)

Status: Closed to Recruitment

PNOC019/NICHE-HGG: A Pilot Trial of Neoadjuvant Checkpoint Inhibition followed by Combination Adjuvant Checkpoint Inhibition in Children and Young Adults with Recurrent or Progressive High Grade Glioma (HGG)

Neuroblastoma

Status: Closed to Recruitment NSW , VIC , WA

LINES: European Low and Intermediate Risk Neuroblastoma (Phase III SIOPEN study)

Brain tumours

Status: Closed to Recruitment NSW , QLD , TAS , VIC , WA , SA , New Zealand

MNP2.0: Molecular Neuropathology 2.0

Hypermutant Cancers

Status: Closed to Recruitment NSW , QLD , SA

Hypermutant Cancers Trial: A Pilot Study of Nivolumab in Paediatric Patients with Hypermutant Cancers

Brain cancer: Medulloblastoma

Status: Closed to Recruitment

SJ ELiOT: Phase 1 Evaluation of LY2606368, a CHK inhibitor, in combination with cyclophosphamide or gemcitabine for children & adolescents with recurrent medulloblastoma tumours.

Brain and solid tumours

Status: Closed to Recruitment

COZMOS: Phase I/Ib trial of Combined 5’azacitidine and carboplatin for recurrent/refractory paediatric brain and solid tumours

High risk haematological malignancy, or a non-malignant disease

Status: Closed to Recruitment

Pαβlo: Paediatric αβ haploidentical transplantation

Leukaemia, solid tumours and brain tumours

Status: Closed to Recruitment NSW , QLD , VIC , WA , SA

PARC: An international phase I/II study evaluating the safety and activity of Pegylated recombinant human Arginase (BCT-100) in Relapsed/refractory cancers of Children and young adults.

Leukaemia: AML and High Risk MDS

Status: Closed to Recruitment

MyeChild 01: International Randomised Phase III Clinical Trial in Children with Acute Myeloid Leukaemia: Incorporating an Embedded Dose Finding Study for Gemtuzumab Ozogamicin in Combination with Induction Chemotherapy

Leukaemia: Acute lymphoblastic leukaemia (MLL rearranged)

Status: Closed to Recruitment

Blin-fant Study: A pilot study to test the feasibility, safety and efficacy of the addition of the BiTE antibody Blinatumomab to the Interfant-06 backbone in infants with MLL-rearranged acute lymphoblastic leukemia: A collaborative study of the Interfant network

Leukaemia: Acute Lymphoblastic Leukaemia (high risk)

Status: Closed to Recruitment

IntReALL HR 2010: International study for treatment of childhood Relapsed high risk ALL (HR-ALL) 2010: A randomized Phase II Study

Leukaemia: Acute Lymphoblastic Leukaemia (high risk)

Status: Closed to Recruitment

FORUM: Allogeneic Stem Cell Transplantation in Children and Adolescents with Acute Lymphoblastic Leukaemia – For Omitting Radiotherapy in the Under Majority age

Lymphoma: Classical Hodgkin Lymphoma

Status: Closed to Recruitment

EuroNet-PHL-C2: European Network of Paediatric Hodgkin Lymphoma Second International Inter-Group Study for Classical Hodgkin Lymphoma in Children and Adolescents

Brain and Spinal Cord Tumours

Status: Closed to Recruitment

AIM BRAIN: Access to Innovative Molecular Diagnostic Profiling for Paediatric Brain Tumours

Solid Tumours: Malignant Rhabdoid Tumour, Atypical Teratoid Rhabdoid Tumour, Neuroblastoma, Osteoscaroma

Status: Closed to Recruitment

NORTH Trial: A phase II study of Panobinostat in Paediatric, Adolescent and Young Adults with Solid Tumours including Neuroblastoma, Osteosarcoma, Malignant Rhabdoid Tumour/Atypical Teratoid Rhabdoid Tumours

Brain Tumor - Diffuse Intrinsic Pontine Glioma (DIPG)

Status: Closed to Recruitment NSW , QLD , VIC , WA , SA , New Zealand

BIOMEDE: Biological Medicine for Diffuse Intrinsic Pontine Glioma Eradication

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