Australian & New Zealand Childrens Haematology/Oncology Group

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Diffuse Midline Gliomas

Status: In Development

PNOC-022 (DMG-ACT) – A Combination Therapy Trial using an Adaptive Platform Design for Children and Young Adults with Diffuse Midline Gliomas including Diffuse Intrinsic Pontine Gliomas at Initial Diagnosis, Post-Radiation Therapy and at Time of Progression.

Ewing Sarcoma

Status: In Development

INTER-EWING- 1: INTERnational scientific program in clinical research to improve outcomes of newly diagnosed EWING sarcoma – trial 1

Acute lymphoblastic leukemia

Status: Open | NSW

Study 10: International collaborative treatment protocol for children and adolescents with acute lymphoblastic leukemia (AIEOP-BFM ALL 2017)

High Grade Glioma

Status: Open | WA

CONNECT 1903: A Pilot and Surgical Study of Larotrectinib for Treatment of Children with Newly-Diagnosed High-Grade Glioma with NTRK Fusion

Diffuse Intrinsic Pontine Glioma (DIPG)

Status: Open | NSW , QLD , VIC , WA , New Zealand

ReRAD: A Phase II Canadian Paediatric Brain Tumour Consortium Study of Re – Irradiation as Treatment of Progressive or Recurrent Diffuse Intrinsic Pontine Glioma

High Grade Glioma(NICHE-HGG)

Status: Open | NSW , QLD , VIC , WA , SA

PNOC019/NICHE-HGG: A Randomized, Double-Blinded, Pilot Trial of Neoadjuvant Checkpoint Inhibition followed by Combination Adjuvant Checkpoint Inhibition in Children and Young Adults with Recurrent or Progressive

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