Australian & New Zealand Childrens Haematology/Oncology Group

Clinical Trials

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High Grade Glioma

Status: Preparing to Open

CONNECT 1903: A Pilot and Surgical Study of Larotrectinib for Treatment of Children with Newly-Diagnosed High-Grade Glioma with NTRK Fusion

Diffuse Intrinsic Pontine Glioma (DIPG)

Status: Open | QLD , VIC

ReRAD: A Phase II Canadian Paediatric Brain Tumour Consortium Study of Re – Irradiation as Treatment of Progressive or Recurrent Diffuse Intrinsic Pontine Glioma

High Grade Glioma(NICHE-HGG)

Status: Preparing to Open

PNOC019/NICHE-HGG: A Randomized, Double-Blinded, Pilot Trial of Neoadjuvant Checkpoint Inhibition followed by Combination Adjuvant Checkpoint Inhibition in Children and Young Adults with Recurrent or Progressive

Progressive high-risk solid tumours or central nervous system tumours

Status: Open | WA

INFORM2 NivEnt: Phase I/II combination study of Nivolumab and Entinostat in children and adolescents with refractory high-risk malignancies

Solid tumour: High risk neuroblastoma

Status: In Development

HR-NBM study: High-Risk Neuroblastoma Study 2 of SIOP-Europa-Neuroblastoma (SIOPEN)

Peripheral neuroblastic tumours

Status: Open | NSW , TAS , VIC , WA

SIOPEN SCI Registry: Prospective Study Registry of Peripheral Neuroblastic Tumours Presenting with Spinal Canal Involvement

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