Australian & New Zealand Childrens Haematology/Oncology Group

Clinical Trials

Viewing: In Development

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Leukaemia, solid tumours and brain tumours

Status: In Development

PARC: An international phase I/II study evaluating the safety and activity of Pegylated recombinant human Arginase (BCT-100) in Relapsed/refractory cancers of Children and young adults.

Brain and solid tumours

Status: In Development

COZMOS: Phase I/Ib trial of Combined 5’azacitidine and carboplatin for recurrent/refractory paediatric brain and solid tumours

Brain cancer: Medulloblastoma

Status: In Development

SJ ELiOT: St Jude – Phase 1 Evaluation of LY2606368, a CHK inhibitor, in combination with cyclophosphamide or gemcitabine for children & adolescents with recurrent medulloblastoma tumours.

Hypermutant Cancers

Status: In Development

Hypermutant Cancers Trial: A Pilot Study of Nivolumab in Paediatric Patients with Hypermutant Cancers

Rhabdomyosarcoma

Status: In Development

Far-RMS: Frontline and Relapse Study in RhabdomyoSarcoma Study

NF-1 associated plexiform neurofibromas or progressive optic pathway gliomas

Status: In Development

TINT: A phase II study of trametinib in paediatric, adolescent and young adult patients with Neurofibromatosis type 1 associated plexiform neurofibromas or progressive optic pathway gliomas.

Peripheral neuroblastic tumours

Status: In Development

SIOPEN SCI Registry: Prospective Study Registry of Peripheral Neuroblastic Tumours Presenting with Spinal Canal Involvement

Solid tumour: High risk neuroblastoma

Status: In Development

HR-NBM study: High-Risk Neuroblastoma Study 2 of SIOP-Europa-Neuroblastoma (SIOPEN)

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