Australian & New Zealand Childrens Haematology/Oncology Group

Clinical Trials

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Hypermutant Cancers

Status: In Development

Hypermutant Cancers Trial: A Pilot Study of Nivolumab in Paediatric Patients with Hypermutant Cancers

Brain cancer: Medulloblastoma

Status: In Development

SJ ELiOT: St Jude – Phase 1 Evaluation of LY2606368, a CHK inhibitor, in combination with cyclophosphamide or gemcitabine for children & adolescents with recurrent medulloblastoma tumours.

Brain and solid tumours

Status: In Development

COZMOS: Phase I/Ib trial of Combined 5’azacitidine and carboplatin for recurrent/refractory paediatric brain and solid tumours

High risk haematological malignancy, or a non-malignant disease

Status: Open | NSW , QLD , VIC , WA , New Zealand

Pαβlo: Paediatric αβ haploidentical transplantation

High-risk cancers

Status: Open | NSW , QLD , TAS , VIC , WA , SA

PRISM: PRecISion Medicine for Children with Cancer

Leukaemia, solid tumours and brain tumours

Status: In Development

PARC: An international phase I/II study evaluating the safety and activity of Pegylated recombinant human Arginase (BCT-100) in Relapsed/refractory cancers of Children and young adults.

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